According to a new study in Vancouver, preschool children with peanut allergies can be treated safely by ingesting a small amount of peanut protein as a medical specialist's guide.
The findings provide confidence to clinicians and hospital allergy specialists that oral immunotherapy is not limited to the study environment.
Edmond Chan, lead author and pediatric allergy specialist, says the technique is embarrassing because many allergy experts fear that they can cause serious allergic reactions. However, he and other scientists and pediatric allergists at British Columbia University and BC Children's Hospital actually say the risks are minimal.
According to their study, only 0.4% of the 270 children who received oral immunotherapy had severe reactions. Meanwhile, 11 children, or 4%, received epinephrine. Researchers found that almost 68% of children had at least one allergic reaction, but 36.3% were mild and 31.1% were moderate.
Children were treated from April 2017 to November 2018 at the age of 9 months to 5 years.
Research results across Canada have been published in the journal "Allergy and Clinical Immunology Journal: Practice".
Oral immunotherapy is a relatively new approach to improving the tolerability of patients by ingesting small amounts of allergenic foods. The dose is gradually increased to the maximum known as the maintenance level and lasts for at least 1 year, even 2 years.
At that point, the child may be ready for a challenge to food. For example, eating a peanut can determine if you are at risk of contracting an allergic antigen.
It has been successful in clinical trials, but Canadian allergy experts are still divided, says Chan.
"There are some allergic respondents who think that they should do it during the investigation, and there are other allergic respondents who think they can deliver to the carefully selected patient from outside the study," says Chan. Allergy experts are not alone in the home.
"I observed several patients going to the United States and received this treatment in a remote clinic.I felt very confused …. They were all available to an allergy specialist.Oh yeah, "No one has caused another allergic reaction."
Chan is one of the people who provide oral immunotherapy that peanut allergy believes is very treatable for young children.
He considers this research to encourage other allergy specialists to consider OIT as a "game changer" and hopes to engage in dialogue to establish national guidelines to ensure safe dialogue.
"Since there are a certain number of allergic responders already on board and already possessing an allergist, not a study, we need to make sure that the patient is safe in entering the office by providing appropriate standards and guidelines."
– By Cassandra Szklarski – Toronto
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