November 19, 2018 Monday
According to a recent study in the United States, babies born to obese mothers are at high risk for liver disease and obesity.
The study was carried out by a researcher at the University of Colorado School of Medicine and published in the current issue of Nature Science.
The researchers found that childhood obesity is a worldwide epidemic, with 57 percent of newly born children expecting to become obese when they turn 35, which is close to 40 percent of the mother's obesity rate. .
To investigate the relationship between maternal obesity and child obesity and obesity, the researchers divided into two groups according to a group of children with an average age of two. The first group was born from an obese mother, and the second group was born from a normal weight mother.
The researchers took stool samples from two groups of infants and placed them in mouse-less mice and bacteria.
Researchers have found that intestinal microbes within the intestines of children born from obese mothers have caused metabolic and metabolic changes in liver and bone marrow cells in mice.
Then, when rats were fed high fat diet, they were more vulnerable to rapid weight gain and the development of nonalcoholic fatty liver disease than other groups.
The study was the first to show that microbes born in the early stages of developing obesity in children play a role in altering microbes in the intestines, said Taylor Soderberg, lead author of the study.
He added that this is the first empirical evidence to support the hypothesis that changes in the intestinal microflora of infants born to obese mothers begin shortly after birth.
Microorganisms living in the intestine are naturally different depending on the incidence of obese mothers and can cause inflammation and other changes in the guts of the children, which increases the risk of later in vivo obesity and nonalcoholic fatty liver disease.
The neonatal intestinal microbes in obese mothers can investigate the possibility of a change in the bowel, which appears to be at risk of lowering the incidence of nonalcoholic fatty liver disease, affecting about 30% of obese children.
Nonalcoholic fatty liver disease affects nearly a quarter of the world's population today, and the US health system alone costs $ 32 billion annually.
This disease often affects foods rich in saturated fats, especially those who are obese as a result of eating fast food, people with diabetes, and people with high cholesterol levels.
This disease can cause serious health problems and sometimes the child's liver cirrhosis results in liver cancer or liver dysfunction.