Thursday , March 30 2023

Transplanting stem cells into the brain can be helpful in the treatment of Parkinson's disease.


Transplanting stem cells into the brain can be helpful in the treatment of Parkinson's disease.

November 10, 2018 – 13:18 AMT

PanARMENIAN.Net – Japanese researchers announced on Friday, November 9, that they have implanted stem cells into the patient's brain in the first phase of an innovative trial for treatment. Parkinson's disease. Kyoto University researchers injected prostate stem (iPS) cells into the brain of a male patient in their 50s. The cells would be differentiated into the brain of a male patient in their 50s, the college said in a press release from

The man has recovered from the surgery after last year's surgery and will continue to monitor for two years, he added. The researchers injected 2.4 million iPS cells into the left side of the patient's brain with a three-hour operation.

If there are no problems in the next six months, 2.4 million cells will be inserted to the right. Healthy donor iPS cells have been developed as precursors of dopamine-producing brain cells that no longer exist in patients with Parkinson's disease.

The surgery was followed by a clinical trial with seven participants between the ages of 50 and 69 years after the university announced in July. It is the first time to implant stem cells into the brain to treat Parkinson's disease.

Associate Professor Takahashi said at a news conference, "According to NHK, I am grateful to the patients for their courage and determination to participate in the test."

Parkinson's disease is a chronic degenerative neurological disease that affects the body's motor nervous system, often causing agitation and other movement disorders. According to the Parkinson & apos; s Disease Foundation, about 10 million people worldwide suffer from this disease.

The available therapies "improve symptoms without slowing or stopping disease progression," the Foundation says. Human trials come after the initial trial of monkeys.

The researchers reported last year that primates with Parkinson's syndrome recovered considerable mobility after iPS cells were inserted into the brain.

They also confirmed that iPS cells were not transformed into tumors for two years after implantation. iPS cells are created by stimulating already mature and specialized cells into juvenile status, basically replicating without the fetus.

Cells can be transformed into various types of cells, and their use is a key area of ​​medical research.

Source link